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Ca Pre-rinse Greatly Increases Plaque and Plaque Fluid F

American Dental Association Foundation, Paffenbarger Research Center, 100 Bureau Drive Stop 8546, National Institute of Standards and Technology, Gaithersburg, MD 20899-8546, USA

^* corresponding author, jvogel{at}nist.gov

Previous studies demonstrated that a Ca pre-treatment greatly increases salivary F from a subsequent NaF rinse. This study examines if these increases are found in plaque and plaque fluid F. Thirteen individuals accumulated plaque before rinsing with: (1) 12 mmol/L NaF (228 µg/g F), (2) 150 mmol/L Ca rinse, or (3) the Ca rinse followed by the F rinse. One hr later, plaque samples were collected, the plaque fluid was recovered, and the plaque residues were extracted 5 times with pH 6.8 or pH 4.8 buffers, and then by acid. The F in each extract after the Ca rinse/F rinse greatly exceeded the corresponding F from the NaF rinse. Consequently, the Ca rinse/F rinse increased the total plaque F and the plaque fluid F by 12x and 5x, compared with the NaF rinse alone. These and the previous salivary results suggest that a Ca pre-treatment may increase the cariostatic effects of topical F agents.

KEY WORDS: fluoride • rinse • plaque • calcium • pre-rinse