Journal of Dental Research, Vol 77, 1767-1771, Copyright © 1998 by International & American Associations for Dental Research Online Journals
Edgard C. Moreno, PhD: a tribute to his major contributions to oral biology research
H. C. Margolis
Department of Biomineralization, Forsyth Dental Center, Boston, Massachusetts 02115, USA.
The seminal contributions of Dr. Edgard C. Moreno to physical chemical
aspects of oral biology research are reviewed, with personal insights
provided by the author. Dr. Moreno has made major contributions to our
understanding of fundamental processes which occur within the oral cavity
and which control the formation of mineralized tissues. These contributions
include extensive research in the areas of: the chemistry of synthetic
calcium phosphates and biominerals, the interaction of salivary proteins
and other molecules of biological interest with calcium phosphate surfaces,
the mechanism of dental caries formation and the effects of fluoride on
this process, the mechanism of dental calculus formation and prevention,
and the mechanism of dental enamel formation.