Journal of Dental Research, Vol 72, 484-489, Copyright © 1993 by International & American Associations for Dental Research Online Journals
Pulp capping with Bioglass and autologous demineralized dentin in miniature swine
B. Oguntebi, A. Clark and J. Wilson
University of Florida Health Science Center, Department of Endodontics, Gainesville 32610-0436.
The purpose of this study was to compare the responses of mechanically
exposed dental pulps which had been capped with three dissimilar materials:
a bioactive ceramic (Bioglass), autologous demineralized dentin matrix
(DDM), and a calcium hydroxide product (Life), with Teflon discs as
controls. Mechanical dental pulp exposures were made after preparation of
deep buccal Class V cavities in 48 teeth in four miniature swine. The
exposures were capped and the cavity preparations restored with zinc
oxide-eugenol (IRM) cement. The animals were killed after 90 days, the
coronal 2/3 of the teeth removed, and sections prepared for either
histological or microradiographic examination. The pulpal inflammatory
reactions and the degree of reparative dentin formation were assessed from
demineralized serial sections. A qualitative assessment of the degree of
mineralization of the reparative dentin was made from microradiographs of
undecalcified sections. The observations suggest that reparative dentin
formation occurs under a variety of pulp-capping materials, but the
structure of the reparative dentin varies with the material and the
condition of the underlying pulp.
