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Journal of Dental Research, Vol 70, 966-969, Copyright © 1991 by International & American Associations for Dental Research Online Journals

ARTICLES

Immunocytochemical evidence for the site of O-methylation in rat dental pulp

K. Inoue, T. Nishino and C. R. Creveling
Department of Oral Anatomy, Okayama University, Dental School, Japan.

Immunocytochemical observations by light and electron microscopy of catechol-O-methyltransferase (COMT) were conducted in dental pulp by use of a specific antibody to soluble rat-liver COMT and the peroxidase-antiperoxidase technique. Immunoreactive deposits were found in macrophages. The pattern of localization suggests that COMT may function in extraneuronal inactivation of catecholamines in dental pulp.




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