Journal of Dental Research, Vol 70, 226-232, Copyright © 1991 by International & American Associations for Dental Research Online Journals
Draft results of a workshop to develop guidelines for studies involving microbial incidence or populations in the oral cavity
M. I. Krichevsky
Microbial Systematics Section, NIDR, NIH, Bethesda, Maryland 20892.
The following five outlines are the results to date of the Workshop held in
Rockville, Maryland, in January, 1990. The topics considered in these
outlines are: (1) validation of immunological and/or nucleic acid
identification probes, (2) cross-calibration of methods and/or laboratories
for multi-laboratory cooperative studies, (3) choosing methods for
identifying or describing microbial populations appropriate to the
scientific question asked, (4) microbial ecology methods (e.g., population
dynamics) for the oral cavity studies, and (5) epidemiological methods
(e.g., incidence, risk factor analysis) for oral microbial studies. Each
topic was considered by two independent groups of participants and later
rationalized into one. These outlines are meant to be working outlines for
evolution of a set of guidelines to advise on designing studies with
microbial incidence and/or population components. We are publishing this
preliminary version to elicit comment and criticism from people who did not
attend the Workshop. (Attendance at the Workshop was necessarily limited by
both space and funds). Some of the topic outlines have been condensed to
save Journal space. The full document is available on request. The next
stage will be an open forum to gather and discuss further amplification of
the "Guidelines", planned for April 17, 1991, Acapulco, Mexico, in
conjunction with the IADR/AADR Meeting. Written comments and requests for
further information should be sent to the Workshop organizer (MIK) at the
above address.(ABSTRACT TRUNCATED AT 250 WORDS)
