Journal of Dental Research, Vol 67, 543-547, Copyright © 1988 by International & American Associations for Dental Research Online Journals

ARTICLES

Homology of glucosyltransferase gene and protein sequences from Streptococcus sobrinus and Streptococcus mutans

R. R. Russell, T. Shiroza, H. K. Kuramitsu and J. J. Ferretti
Dental Research Unit, Royal College of Surgeons of England, Kent, United Kingdom.

The sequences of glucosyltransferase genes from Streptococcus sobrinus (gtfI) and Streptococcus mutans (gftB) were compared and show a high degree of homology. There is a 57.7% homology of nucleotides in the genes and a 56.7% homology of amino acids in the deduced protein sequences. The G + C content for the protein-coding region is 43.6% for S. sobrinus and 41.2% for S. mutans. Internal repeating sequences present in both proteins exhibit some difference in sequence pattern.

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