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Journal of Dental Research, Vol 67, 1402-1404, Copyright © 1988 by International & American Associations for Dental Research Online Journals

ARTICLES

Changes of secretory ameloblasts in mini-pig fetuses exposed to ethanol in vivo

M. E. Matthiessen and P. Romert
Anatomy Department A, Panum Institute, University of Copenhagen, Denmark.

After addition of ethanol to the ordinary fodder of pregnant mini-pigs, ultrastructural changes were found in secretory ameloblasts from tooth germs of their mid-term fetuses. Compared with controls, many mitochondria showed abnormal shape and size, and some exhibited deposition of paracrystalline material in the matrix. An abnormal deposition of stippled material intercellularly was also observed. These changes were interpreted as signs of an abnormal secretory function.




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