Journal of Dental Research, Vol 67, 37-43, Copyright © 1988 by International & American Associations for Dental Research Online Journals
Sialographic images of pathological changes in the mouse parotid gland
M. Domon, T. Kurabayashi and Y. Shiga
Department of Dental Radiology, Tokyo Medical and Dental University, Japan.
In order to correlate pathological changes of mouse parotid glands with
their sialographic images, we conducted studies on mice with known
pathological changes: mice with Stensen's duct ligated, NZB mice with a
systemic auto-immune disease, and aged mice. The sialographic images were
found to be specific for the pathological changes: The glands after
ligation of Stensen's duct were characterized by dilated, large excretory
ducts with a reduced system of peripheral ducts; the glands of NZB mice
showed lobular leakage of the contrast medium from small excretory ducts;
and the glands of aged mice showed a great reduction in the ductal system.
It is concluded that sialography yields useful information on the
pathological changes of the ductal systems in the mouse parotid gland.
