Journal of Dental Research, Vol 66, 1730-1734, Copyright © 1987 by International & American Associations for Dental Research Online Journals

ARTICLES

Fluoride in saliva and plaque following use of fluoride-containing mouthwashes

R. M. Duckworth, S. N. Morgan and A. M. Murray
Unilever Research, Port Sunlight Laboratory, Bebington, Wirral, Merseyside, England.

The sensitivity of methodology for measuring the concentration of fluorine species in saliva and in plaque has been tested. Human subjects mouth-rinsed daily with aqueous solutions of NaF and Na2FPO3. Samples of unstimulated whole saliva and of plaque were collected twice weekly at least 18 hr after treatment application. Oral fluoride concentrations rose from placebo values for approximately two weeks before attaining equilibrium and returned to baseline when daily mouthrinsing was stopped. Mean elevated oral fluoride concentrations increased significantly with increasing applied NaF concentration in the range 0-1000 ppm F (0-0.053 mol/L). There appeared to be a linear relationship between saliva and plaque fluoride. The ability of fluoride treatments to sustain elevated oral fluoride levels between daily applications may be of major importance in caries control.

This article has been cited by other articles:

				P. Stoodley, J. Wefel, A. Gieseke, D. deBeer, and C. von Ohle Biofilm Plaque and Hydrodynamic Effects on Mass Transfer, Fluoride Delivery and Caries J Am Dent Assoc, September 1, 2008; 139(9): 1182 - 1190. [Abstract] [Full Text] [PDF]

				H. Koo Strategies to Enhance the Biological Effects of Fluoride on Dental Biofilms Adv. Dent. Res., July 1, 2008; 20(1): 17 - 21. [Full Text] [PDF]

				H. Koo Strategies to Enhance the Biological Effects of Fluoride on Dental Biofilms Advances in Dental Research, July 1, 2008; 20(1): 17 - 21. [Full Text] [PDF]

				J. Welin-Neilands and G. Svensater Acid Tolerance of Biofilm Cells of Streptococcus mutans Appl. Envir. Microbiol., September 1, 2007; 73(17): 5633 - 5638. [Abstract] [Full Text] [PDF]

				W. H. Bowen DO WE NEED TO BE CONCERNED ABOUT DENTAL CARIES IN THE COMING MILLENNIUM? Crit. Rev. Oral. Biol. Med., March 1, 2002; 13(2): 126 - 131. [Abstract] [Full Text]

				W. H. Bowen DO WE NEED TO BE CONCERNED ABOUT DENTAL CARIES IN THE COMING MILLENNIUM? Critical Reviews in Oral Biology & Medicine, March 1, 2002; 13(2): 126 - 131. [Abstract] [Full Text] [PDF]

				R.M. Duckworth, Y. Jones, J. Nicholson, A.P.M. Jacobson, and I.G. Chestnutt Studies on Plaque Fluoride After Use of F-Containing Dentifrices Advances in Dental Research, July 1, 1994; 8(2): 202 - 207. [Abstract] [PDF]

				R.M. Duckworth, S.N. Morgan, and C.K. Burchell Fluoride in Plaque Following Use of Dentifrices Containing Sodium Monofluorophosphate Journal of Dental Research, February 1, 1989; 68(2): 130 - 133. [Abstract] [PDF]