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Journal of Dental Research, Vol 66, 50-56, Copyright © 1987 by International & American Associations for Dental Research Online Journals

ARTICLES

Immunochemical and biochemical studies of human enamel proteins during neonatal development

M. Zeichner-David, M. MacDougall, J. Vides, M. L. Snead, H. C. Slavkin, S. B. Turkel and Z. Pavlova

The present communication provides descriptions of the developmental, biochemical, and immunological properties of the human enamel extracellular matrix proteins. We report the isolation and partial characterization of the major human enamel proteins, the production of polyclonal antibodies directed against the human enamelins, and a comparison between the immunogenicity of enamelins and amelogenins from human and mouse enamel extracellular matrices. Our results indicate that although enamelins and amelogenins share some epitopes, each one of these proteins appears to invoke a different degree of immunogenicity.




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Journal of Dental Research ® Critical Reviews (1990-2004)
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