Journal of Dental Research, Vol 65, 1064-1070, Copyright © 1986 by International & American Associations for Dental Research Online Journals
A histological assessment of the initial healing response adjacent to porous-surfaced, titanium alloy dental implants in dogs
D. A. Deporter, P. A. Watson, R. M. Pilliar, A. H. Melcher, J. Winslow, T. P. Howley, P. Hansel, C. Maniatopoulos, A. Rodriguez, D. Abdulla and al. et
We report here the results of a histological assessment of the initial
healing response following implantation into the dog mandible of a
porous-surfaced, titanium alloy endosseous dental implant. Two implants
were placed in edentulous areas on each side of the mandible of each dog
and covered with a full-thickness mucoperiosteal flap. The implant sites on
one side of the mandible were allowed to head for four weeks, while those
on the other side were allowed to head for eight weeks before the animals
were killed. Histological specimens were obtained and assessed both
qualitatively and by computer-assisted morphometry. All but one of the 24
implants were well-tolerated and healed with a variable ingrowth of bone
into the porous-surface geometry. The histomorphometric measurements
revealed that bone ingrowth had reached a plateau by four weeks of initial
healing.
