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Journal of Dental Research, Vol 65, 1445-1448, Copyright © 1986 by International & American Associations for Dental Research Online Journals


ARTICLES

In vivo and in vitro study of the effects of vitamin A deficiency on rat third molar development

S. S. Harris and J. M. Navia

We have examined the effect of in vivo vitamin A status on subsequent rat third molar formation and mineralization in an in vitro organ culture system. Vitamin A deficiency imposed during an eight-day in vitro period caused effects very similar to those of vitamin A deficiency imposed on rats in vivo. Analysis of the data also demonstrates that retinoic acid is capable of reversing the interference in mineralization of third molars induced by vitamin A deficiency in the organ culture system.


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A. R. SILVESTRI JR. and I. SINGH
The unresolved problem of the third molar: Would people be better off without it?
J Am Dent Assoc, April 1, 2003; 134(4): 450 - 455.
[Abstract] [Full Text] [PDF]




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