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Journal of Dental Research, Vol 65, 1445-1448, Copyright © 1986 by International & American Associations for Dental Research Online Journals
ARTICLES |
S. S. Harris and J. M. Navia
We have examined the effect of in vivo vitamin A status on subsequent rat third molar formation and mineralization in an in vitro organ culture system. Vitamin A deficiency imposed during an eight-day in vitro period caused effects very similar to those of vitamin A deficiency imposed on rats in vivo. Analysis of the data also demonstrates that retinoic acid is capable of reversing the interference in mineralization of third molars induced by vitamin A deficiency in the organ culture system.
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