Journal of Dental Research, Vol 65, 1410-1414, Copyright © 1986 by International & American Associations for Dental Research Online Journals
In vivo bovine enamel remineralization and fluoride uptake from two dentifrices containing different fluoride concentrations
H. J. De Kloet, R. A. Exterkate, H. E. Rempt and J. M. Ten Cate
In this study, the differences in lesion remineralization and fluoride
uptake after brushing with a 300 ppm F or a 1000 ppm F dentifrice (as NaF)
were investigated. Twenty volunteers with partial dentures in their lower
jaws were divided into two groups. Bovine enamel slabs with artificial
lesions were mounted in the dentures. After a test period of six weeks, the
slabs were taken out and analyzed. There was no statistically significant
difference between the two groups, in F-uptake and susceptibility of the
enamel to demineralization, although the findings favored the 1000 ppm F
toothpaste. The microradiograms in the 300 ppm F group showed lesions more
pronounced than those in the 1000 ppm group. The present study cannot
support the presumption that the fluoride content of regular NaF
dentifrices can be lowered to 300 ppm F without undesirable effects on
lesion arrest and remineralization.
