Journal of Dental Research, Vol 64, 82-84, Copyright © 1985 by International & American Associations for Dental Research Online Journals
Enhanced fluoride uptake from mouthrinses
Y. C. Hong, L. C. Chow and W. E. Brown
It has been shown in laboratory and animal studies that tooth enamel
becomes considerably more reactive toward low levels of fluoride after
receiving pre-treatment which forms dicalcium phosphate dihydrate (DCPD) in
the enamel as an intermediate. This in vitro study was undertaken to
determine the effect on human enamel fluoride uptake of incorporating
DCPD-forming rinses into a conventional fluoride rinsing program. In one
group, enamel samples received a one-minute rinse with 0.2% NaF each day
for 20 days. Samples in the second group were treated identically, except
that they were also given a one-minute DCPD-forming rinse prior to the
first, sixth, eleventh, and sixteenth fluoride rinses. At the end of the
rinsing program, all samples were washed in 1 M KOH to remove labile
fluorides. The enamel biopsy data showed that the fluoride uptake resulting
from 0.2% NaF alone was not statistically significant, whereas uptake
produced by the DCPD-forming plus NaF rinses was significant. The results
suggest that the DCPD-forming rinse may improve the efficacy of fluoride
rinse programs.
