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Journal of Dental Research, Vol 64, 1319-1321, Copyright © 1985 by International & American Associations for Dental Research Online Journals

ARTICLES

Plaque inhibition by sustained release of chlorhexidine from removable appliances

M. Friedman, D. Harari, H. Raz, G. Golomb and L. Brayer

We studied the effectiveness of a sustained-release delivery system for chlorhexidine in plaque prevention. A clinical trial in a group of eight students wearing orthodontic appliances coated by ethyl cellulose polymer containing the drug demonstrated that plaque accumulation was decreased for a period of four days. All oral procedures had been withdrawn during the clinical study. No side-effects of chlorhexidine, such as tooth staining and unpleasant taste, were observed.




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