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Journal of Dental Research, Vol 63, 1108-1115, Copyright © 1984 by International & American Associations for Dental Research Online Journals

ARTICLES

Ultrastructural changes in the cementoblasts of rat molars after injection of vincristine

S. Takuma, T. Sawada, S. Yama and T. Yanagisawa

Cytological changes in the cementoblasts of rats treated with vincristine were investigated. Accumulation of secretion granules indicated a disturbed secretory mechanism in the cells. Conspicuous dilation of the endoplasmic reticulum suggested disturbance in the transport of substances from the rough endoplasmic reticulum to the Golgi elements. These disturbances were interpreted to be a result of disruption of microtubules.




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