Journal of Dental Research, Vol 63, 1072-1074, Copyright © 1984 by International & American Associations for Dental Research Online Journals
Influence of serum on cultured murine tooth organ allotransplants
G. R. Riviere
Previous investigations indicated that in vitro culture of fetal tooth
germs before allotransplantation prolonged graft survival. This study
assessed the influence of different sources of serum in culture medium on
post-transplant development of neonatal tooth organs. The results indicate
that recipient-strain serum, but not donor-strain serum or calf serum,
increased tooth survival compared with that of uncultured controls, which
were rejected by the fourteenth post-transplant day. The survival curve for
cultured tooth organs was shifted to the right by two days. No tooth
transplant survived beyond three wk.