Journal of Dental Research, Vol 63, 1037-1039, Copyright © 1984 by International & American Associations for Dental Research Online Journals

ARTICLES

The ureolytic microflora of immature dental plaque before and after rinsing with a urea-based mineralizing solution

I. H. Gallagher, E. I. Pearce and E. M. Hancock

Ureolytic bacteria were detected in the plaque flora of six subjects, and included members of the genera Actinomyces, Bifidobacterium, Staphylococcus, and Streptococcus. Proportions of these organisms did not change after subjects mouthrinsed thrice daily for four days with a plaque-mineralizing solution which contained urea and mono-fluorophosphate. The effectiveness of this rinse depends on the rapid metabolism of urea to alkali by plaque organisms, causing fluoridated apatite to precipitate in the matrix. Analysis of our data suggests that a numerically minor component of the flora, with a high turnover rate, is responsible for most of the ureolysis and the subsequent mineral precipitation.

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