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Journal of Dental Research, Vol 63, 665-669, Copyright © 1984 by International & American Associations for Dental Research Online Journals

ARTICLES

Collagen and prostaglandin synthesis in force-stressed periodontal ligament in vitro

G. W. Duncan, E. H. Yen, E. T. Pritchard and D. M. Suga

A periodontal organ culture system capable of receiving orthodontic type forces was developed. Histological, radioautographical, collagen, and prostaglandin synthetic data demonstrated the vitality of the organ over a 24-hour period of culture. Significant increases in the proportion of type III collagen synthesized during periods of active stress were found, but no alterations in relative levels of prostaglandins synthesized during periods of force application were discernible.




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