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Journal of Dental Research, Vol 63, 614-617, Copyright © 1984 by International & American Associations for Dental Research Online Journals

ARTICLES

Saliva secretion from the rat submandibular gland after retrograde infusion of radiographic contrast media

E. Qwarnstrom, L. Bodner, B. Baum, A. Hand and K. A. Omnell

Rat submandibular saliva was collected at various times after retrograde infusion of water-soluble (Renografin 60%) or lipid-soluble (Lipiodol UF) radiographic contrast medium. Significant alterations in flow rate occurred following heavy parenchymal filling with both types of contrast media. Occasional changes in protein concentration, lactoperoxidase activity, and K+ levels were also noted. These changes were relatively mild and transient, and gland function had generally returned to normal by one wk after infusion. No alterations in glandular function were detected after infusion of contrast medium to a degree (ductal filling) comparable to that usually employed in clinical sialography.




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