Journal of Dental Research, Vol 63, 1355-1359, Copyright © 1984 by International & American Associations for Dental Research Online Journals
Effects of sequential calcium phosphate-fluoride rinses on dental plaque, staining, fluoride uptake, and caries in rats
R. J. Shern, L. C. Chow, K. M. Couet, A. Kingman and W. E. Brown
Oral rinses which included (1) an acidic calcium phosphate solution
containing 0.7 M Ca, 1.9 M PO4, and saturated with respect to CaHPO4 .
2H2O, and with a pH of 2.0, followed by (2) a 0.52 M fluoride solution,
from NaF or SnF2, were provided to rats once daily for seven days. The
investigation consisted of two studies: In the first study, the amounts of
dental plaque on the tooth surfaces and fluoride concentrations in the
outer enamel were assessed seven days after the last treatment; in the
second study, the extent of dental caries was evaluated seven weeks after
the last treatment. All rinse sequences containing fluoride provided
significant caries protection. The acidic calcium phosphate treatment
markedly enhanced the ability of the enamel to acquire fluoride without
change of surface morphology. Only the rinse sequences that included
stannous fluoride showed significant plaque suppression.
