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Journal of Dental Research, Vol 62, 1009-1012, Copyright © 1983 by International & American Associations for Dental Research Online Journals

ARTICLES

Phase variation of hyaluronidase-producing peptostreptococci associated with periodontal disease

Y. C. Tam and E. C. Chan

Peptostreptococci isolated from diseased periodontal pockets produced large amounts of extracellular hyaluronidase throughout their growth cycle. Phase variants, obtained by re-streaking aged colonies of the wild types, had different colonial morphology and shorter generation times. These variants produced less hyaluronidase, and enzyme production occurred only during the early stationary phase.


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