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Journal of Dental Research, Vol 62, 877-881, Copyright © 1983 by International & American Associations for Dental Research Online Journals

ARTICLES

The role of cyclic AMP, calcium, and prostaglandins in the induction of osteoclastic bone resorption associated with experimental tooth movement

K. Yamasaki

Administration of imidazole and verapamil inhibited the appearance of osteoclasts and bone resorption induced by experimental tooth movement in rats. On the other hand, administration of theophylline and ouabain enhanced the appearance of osteoclasts. A mixed solution of DB cyclic AMP and A-23187 injected in gingiva near the orthodontically-treated teeth caused enhancement of the appearance of osteoclasts and bone resorption.


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M. L. Jones, J. Hickman, J. Middleton, J. Knox, and C. Volp
A Validated Finite Element Method Study of Orthodontic Tooth Movement in the Human Subject
J. Orthod., March 1, 2001; 28(1): 29 - 38.
[Abstract] [Full Text] [PDF]


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