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Journal of Dental Research, Vol 62, 803-805, Copyright © 1983 by International & American Associations for Dental Research Online Journals

ARTICLES

Nuclear magnetic resonance spectroscopic studies of the interaction of phospholipids with stabilizing lysosome agents

S. Fujisawa, Y. Kadoma and E. Masuhara

The interaction between phospholipids and stabilizing lysosome agents such as acetylsalicylic acid (ASA), colchicine (CC), prednisolone (PD), etc., was studied using NMR spectroscopy. The peak intensity of protons arising from these compounds was reduced in liposomes containing lecithin and various agents with a molar ratio of 1:1 in D2O. The reduced percentage of protons in the agents differed due to their molecular structures: ASA was about 20%, CC about 30%, and PD about 100%.




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