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Journal of Dental Research, Vol 62, 575-577, Copyright © 1983 by International & American Associations for Dental Research Online Journals

ARTICLES

Prednisolone clearance: a possible determinant for glucocorticoid efficacy in patients with oral vesiculo-erosive diseases

F. Lozada, F. J. Frey and L. Z. Benet

The pharmacokinetics of prednisolone were determined in 12 patients with oral vesiculo-erosive diseases. The bioavailability of prednisone in these patients exhibited a low intersubject variability, while the metabolic clearance rate of total and of unbound prednisolone varied considerably from patient to patient.


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M.A. Gonzalez-Moles and C. Scully
Vesiculo-erosive Oral Mucosal Disease--Management with Topical Corticosteroids: (2) Protocols, Monitoring of Effects and Adverse Reactions, and the Future
J. Dent. Res., April 1, 2005; 84(4): 302 - 308.
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