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Journal of Dental Research, Vol 62, 537-539, Copyright © 1983 by International & American Associations for Dental Research Online Journals

ARTICLES

Effect of indomethacin on the blood flow of the rabbit submandibular gland

A. Fazekas, E. Posch and T. Zelles

Effects of the stimulation of the chorda tympani and acetylcholine infused into the artery of the gland were studied on the blood flow and saliva secretion of the rabbit submandibular gland before and after indomethacin treatment. The enhancement of blood flow and saliva secretion was less apparent after indomethacin than before. Results suggest that endogenous prostaglandins are also involved in the mechanism of the augmentation of blood flow and saliva secretion produced by the stimulation of the chorda tympani in the rabbit submandibular gland.




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