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Journal of Dental Research, Vol 62, 1179-1181, Copyright © 1983 by International & American Associations for Dental Research Online Journals

ARTICLES

Use of bacteriophage-resistant mutants to study Actinomyces viscosus cell surface receptors

C. A. Tylenda, P. E. Kolenbrander and A. L. Delisle

Spontaneously occurring bacteriophage-resistant mutants of Actinomyces viscosus were isolated. The mutants exhibited altered coaggregation patterns with streptococci. From analysis of the data, it appears that a cell surface structure on A. viscosus may function both as a phage receptor and as a binding site for co-aggregation with certain oral streptococci. These mutants will be valuable in the study of surface structures that mediate one type of the cell-to-cell interactions that occur between these two important groups of oral bacteria.




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