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Journal of Dental Research, Vol 62, 1054-1057, Copyright © 1983 by International & American Associations for Dental Research Online Journals

ARTICLES

A biochemical study of two bifunctional reagents as alternatives to formocresol

D. M. Ranly and E. P. Lazzari

Two bifunctional reagents, glutaraldehyde and dimethylsuberimidate, were compared to formaldehyde with respect to fixation and modification of protein. Glutaraldehyde proved the superior fixative based on cross-linking and enzyme degradation assays. An immunoprecipitation assay suggests that the reaction products of glutaraldehyde may have altered antigenicity.




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