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Journal of Dental Research, Vol 61, 1010-1013, Copyright © 1982 by International & American Associations for Dental Research Online Journals

ARTICLES

The effect of 5,5'-diphenylhydantoin on the metabolism of 17 beta-estradiol by rat oral mucosa

J. Vittek, P. R. Munnangi, G. G. Gordon, S. C. Rappaport and A. L. Southren

Systemic pretreatment of rats with 5,5'-diphenylhydantoin (DPH) or its addition into an in vitro assay increases microsomal hydroxylation of 17 beta-estradiol. This increase depends on the concentration of DPH in the microsomal cell compartment.




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