Journal of Dental Research, Vol 61, 1458-1460, Copyright © 1982 by International & American Associations for Dental Research Online Journals
Extraskeletal implantation of a porous hydroxyapatite ceramic
J. F. Piecuch
Coralline replamineform hydroxyapatite implants were placed in canine
subcutaneous tissues in an attempt to clarify whether the hydroxyapatite
matrix acted as a passive matrix for osseous ingrowth when placed in some
inherent bone induction capacity. The implants were well-tolerated and
elicited no deleterious host response. Connective tissue rapidly
infiltrated the pores, but no evidence of bone formation was noted in any
of the specimens. It was concluded that this implant material does not act
to induce bone formation.