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Journal of Dental Research, Vol 61, 1451-1453, Copyright © 1982 by International & American Associations for Dental Research Online Journals

ARTICLES

Relationship between frequency of pilocarpine administration and salivary IgA level

D. J. Smith, M. A. Taubman, J. L. Ebersole and W. King

The effect of repetitive administration of pilocarpine nitrate on the salivary volume and salivary IgA concentration was studied in the NIH white hamster. One and one-half to three-fold increases in salivary volume, coupled with decreases of 1/3 to 2/3 in IgA concentration, occurred as the frequency of administration of pilocarpine increased.




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