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Journal of Dental Research, Vol 60, 860-864, Copyright © 1981 by International & American Associations for Dental Research Online Journals

ARTICLES

Binding of eugenol and o-ethoxybenzoic acid to bovine serum albumin

S. Fujisawa and E. Masuhara

The binding constants (log K) of eugenol, o-ethoxy-benzoic acid, and their analogues, plus other organic compounds widely used in dentistry with bovine serum albumin, were examined with respect to the partition coefficients of these compounds in octanol-water (log P). Linear relationships between log K and log P values were obtained with high relative coefficients. Eugenol and o-ethoxybenzoic acid showed a relatively large log K value.




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