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Journal of Dental Research, Vol 60, 770-775, Copyright © 1981 by International & American Associations for Dental Research Online Journals

ARTICLES

In vivo enamel fluoride uptake from and caries inhibition by topical fluoride agents

M. Gibbs, D. H. Retief, E. L. Bradley, R. E. Taylor and A. R. Walker

Acidulated phosphate fluoride (APF), Duraphat or Fluor Protector, was applied to the molar teeth of rats fed a cariogenic diet. The first maxillary molar teeth were subjected to a microbiopsy procedure for fluoride analysis and the mandibular molars scored for caries. All three topical fluoride agents produced a significant increase in the fluoride content of the outermost 5.0 micron of enamel. Only APF produced a significant reduction in caries incidence at all sites.




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