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Journal of Dental Research, Vol 60, 756-762, Copyright © 1981 by International & American Associations for Dental Research Online Journals

ARTICLES

Rapid quantitative determination of the effect of antiplaque agents and antisera on the growth, acid production, and adherence of Streptococcus mutans

J. E. Ciardi, A. B. Rosenthal and W. H. Bowen

A rapid quantitative in vitro assay measured the effects of antiplaque agents and antiserum on growth and sucrose-mediated adherence of radio-labeled S. mutans 6715. Acid production was measured by change in pH. In this assay the primary effect of chlorhexidine and fluoride was bacteriostasis and inhibition of acid production, respectively; the primary effect of dextran, dextranase, and specific antiserum was inhibition of sucrose-mediated adherence.




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