JDR JDR Most Cited Articles
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Greenhill, J. D.
Right arrow Articles by Pashley, D. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Greenhill, J. D.
Right arrow Articles by Pashley, D. H.

Journal of Dental Research, Vol 60, 686-698, Copyright © 1981 by International & American Associations for Dental Research Online Journals

ARTICLES

The effects of desensitizing agents on the hydraulic conductance of human dentin in vitro

J. D. Greenhill and D. H. Pashley

The hydrodynamic theory of dentin sensitivity states that a stimulus applied at the orifice of exposed dentinal tubules causes movement of tubular fluid which stimulates nerve receptors. The fluid should obey principles of fluid movement through capillary tubes. Any decrease in the functional radius of the dentinal tubules should greatly reduce the rate of fluid flow, thus reducing dentinal sensitivity. The purpose of this study was to evaluate the ability of agents that have been used previously for clinical dentin desensitization to reduce the rate of fluid flow through dentin in vitro. Dentin discs prepared from extracted human third molars were treated with 50% citric acid to remove debris from tubular orifices. After placing the discs in a split chamber device, the rate at which buffer solution could filter across the dentin under 240 cm of water pressure was measured. The occlusal side of the disc was then treated with an agent thought to desensitize dentin to determine if it reduced fluid flow rate. Discs that had more than a 50% reduction in flow rate were examined by scanning electron microscopy to determine if those agents that decreased fluid flow also partially occluded tubular orifices. This in vitro model provided a useful quantitative method for screening a host of preparations that have been used in the past to decrease dentin sensitivity.


This article has been cited by other articles:


Home page
 Journal of the American Dental AssociationHome page
R. Orchardson and D. G. Gillam
Managing dentin hypersensitivity.
J Am Dent Assoc, July 1, 2006; 137(7): 990 - 998.
[Abstract] [Full Text] [PDF]

Home page
 J. Dent. Res.Home page
F.R. Tay, D.H. Pashley, Y.F. Mak, R.M. Carvalho, S.C.N. Lai, and B.I. Suh
Integrating Oxalate Desensitizers with Total-etch Two-step Adhesive
J. Dent. Res., September 1, 2003; 82(9): 703 - 707.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
IADR Journals Advances in Dental Research ®
Journal of Dental Research ® Critical Reviews (1990-2004)
Copyright © 1981 Institutional Access Guidelines