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Journal of Dental Research, Vol 60, 174-181, Copyright © 1981 by International & American Associations for Dental Research Online Journals


ARTICLES

Kinetics of cell proliferation and migration associated with orthodontically-induced osteogenesis

W. E. Roberts and D. C. Chase

Cell kinetics of rat molar periodontal ligament (PDL) during orthodontically-induced osteogenesis revealed: 1) primary growth fraction of 59%, 2) proliferating cells from throughout the PDL migrate toward the bone surface, 3) preosteoblasts, capable of forming osteoblasts without synthesizing DNA, are present in the PDL, 4) osteoblasts are derived from local PDL cells, and 5) cell death is a characteristic feature of the osteogenic response.


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