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Journal of Dental Research, Vol 60, 44-49, Copyright © 1981 by International & American Associations for Dental Research Online Journals

ARTICLES

The biocompatibility of dental implant materials measured in an animal model

D. A. Garcia, T. M. Sullivan and D. M. O'Neill

The biocompatibility of two implant materials, vitallium and poly-methyl methacrylate (PMMA), was evaluated in an animal model in which bone formation and resorption are independent of each other. Neither material accelerated resorption, but formation was inhibited 12% by vitallium and 38% by PMMA. When three PMMA preparations varying in monomer content were tested, the data exhibited a dose-response relation, suggesting that inhibition of bone formation was due to the presence of residual monomer.


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