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Journal of Dental Research, Vol 59, 186-191, Copyright © 1980 by International & American Associations for Dental Research Online Journals

ARTICLES

Subcutaneously implanted alginate as a continuous-release source of fluoride

G. M. Whitford, J. Ekstrand, R. S. Callan and D. E. Pearson

The fluoride concentrations of seven brands of alginate ranged from 8600 to 30,500 ppm. In acute and chronic in vivo studies, fluoride was continuously released from subcutaneously implanted alginate cylinders for up to three weeks. This technique is a simple and economical method for elevating soft and hard tissue fluoride levels.




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