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Journal of Dental Research, Vol 59, 1620-1626, Copyright © 1980 by International & American Associations for Dental Research Online Journals
ARTICLES |
M. W. Mao and S. Rosen
In this study, we induced a number of mutants of S. mutans differing in their abilities to synthesize glucan and produce acid. When tested for cariogenicity in gnotobiotic rats, "high pH" mutants caused less caries, but could not supplant a cariogenic parent strain.
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