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Journal of Dental Research, Vol 59, 87-96, Copyright © 1980 by International & American Associations for Dental Research Online Journals

ARTICLES

Experimentally induced alterations in periapical tissues of the cat

M. Torabinejad and R. D. Kiger

Ten cats were immunized with subcutaneous injections of keyhole limpet hemocyanin (KLH). After it was determined that the experimental animals had developed circulating antibodies to KLH, challenge doses of KLH were administered via the root canal system. The radiographic and histologic findings suggest that antigen-antibody complex reactions can occur in periapical tissues of teeth, and that they can play a role in the pathogenesis of periapical lesions. In contrast, no radiographic and histologic changes were noted in non-immunized cats.


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[Abstract] [Full Text] [PDF]


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