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Journal of Dental Research, Vol 59, 2-10, Copyright © 1980 by International & American Associations for Dental Research Online Journals

ARTICLES

Identification of collagenase in cultured blood mononuclear cells

J. W. Simpson, B. F. Mackler, P. O'Neill and M. L. Mailman

Mononuclear cells isolated from peripheral whole blood were fractionated by erythrocyte-rosetting into T cells and non-T cell subpopulations which were tested for collagenase-producing capacity. Mononuclear cells and purified T lymphocytes, as well as non-T (B) lymphocytes, produced collagenase during serum-free culture. Removal of the macrophages from the non-T cells did not affect collagenase production by lymphocytes.




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Journal of Dental Research ® Critical Reviews (1990-2004)
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