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Journal of Dental Research, Vol 58, 1634-1639, Copyright © 1979 by International & American Associations for Dental Research Online Journals


ARTICLES

A comparison of the effects of endotoxin upon fibroblast proliferation and macromolecular syntheses

R. E. Singer and W. G. Dutton

The effects of Escherichia coli endotoxin upon mouse L929 cell proliferation, DNA synthesis, protein synthesis, and proline incorporation were determined. It was found that a level of endotoxin which inhibited cell proliferation prompted a similar inhibition of DNA synthesis and overall cell protein synthesis. In contrast, endotoxin was shown to inhibit incorporation of proline into cell protein to a significantly greater extent.





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Journal of Dental Research ® Critical Reviews (1990-2004)
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