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Journal of Dental Research, Vol 58, 2344-2352, Copyright © 1979 by International & American Associations for Dental Research Online Journals
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L. R. Brown, B. F. Mackler, B. M. Levy, T. E. Wright, S. F. Handler, J. S. Moylan, D. H. Perkins and H. J. Keene
The nature and extent of the immune dysfunctions in 20 immunodeficient patients, as well as the immunocompetence of 22 control subjects, were verified by cell-mediated responsiveness and immunoglobulin quantitations. Comparisons of the microbial composition of supragingival plaque between the two populations showed that a greater number of immunodeficient than control subjects harbored Candida sp. and Staphylococcus sp. Conversely, a lower number of immunodeficient than control subjects harbored Streptococcus mutans. Also, patients with immune dysfunctions had a lower dental caries experience than their immunocompetent counterparts.
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