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Journal of Dental Research, Vol 57, 412-417, Copyright © 1978 by International & American Associations for Dental Research Online Journals

ARTICLES

Diet-induced arteriopathies in the rabbit aorta and oral vasculature

S. Dreizen, M. H. Stern and B. M. Levy

Advanced atherosclerosis in the form of fibro-fatty intimal plaques has been produced in the rabbit aorta and oral vasculature (labial, lingual, gingival, palatal, periodontal and alveolar arteries) by dietary means. The animals were fed a hypercholesteremic diet and a normocholesteremic diet on alternate months for two years. In the aorta and in many of the oral vessels, the formation of the intimal atheromas was paralleled by a degeneration of the tunica media. The lingual arteries rivaled the aorta and coronary arteries in vulnerability to the diet-induced arteriopathies.




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