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Journal of Dental Research, Vol 57, 402-411, Copyright © 1978 by International & American Associations for Dental Research Online Journals

ARTICLES

Effects of craniofacial structures on mouse palatal closure in vitro

L. Brinkley, G. Basehoar and J. Avery

Heads of Swiss-Webster mouse fetuses of four ages spanning days 12-13 of gestation, were partially dissected by removing the brain (B), tongue (T) and mandible (M) alone or in combination (BT, BM, BTM). Preparations were suspended in a gassed, circulating culture system such that palatal closure must take place against gravity. Closure occurred earlier than in vivo and required the posterior half of the mandible be intact and the tongue removed.




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