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Journal of Dental Research, Vol 57, 365-372, Copyright © 1978 by International & American Associations for Dental Research Online Journals

ARTICLES

The effects of cadmium on the growth of some oral microorganisms and their ability to bind cadmium

D. Beighton and W. A. McDougall

All seven oral Actinomycetaceae tested grew in broth containing 10 microgram/ml Cd. After 24 hours' growth A viscosus WVU 626 bound nearly 20 microgram Cd/mg dry wt. The amount of Cd bound varied during the growth cycle, being maximal (90 to 100 microgram/mg dry wt.) after 5 hours' growth. Addition of 50 microgram/ml chloramphenicol to actively growing cells inhibited further Cd binding. In contrast S mutans FA1 was greatly inhibited by 2.5 microgram/ml Cd and bound only 1.3 microgram Cd/mg after 24 hours' growth in broth containing 2.5 microgram/ml Cd.




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