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J Dent Res 57 (11): 1016-1018,
Copyright © 1978 International & American Associations for Dental Research Online Journals


Articles

Cellular regulation of the metabolism of androgens in rat oral mucosa: I. Effect of medroxyprogesterone acetate (MPA) on the soluble supernatant (cytosol) activating microsomal delta4-3-ketosteroid-5alpha-reductase and 17beta-hydroxysteroid oxidoreductase enzyme systems

J Vittek, SC Rappaport, GG Gordon, and AL Southren

Soluble supernatant (cytosol) of rat oral mucosa was found to contain a factor accelerating the activity of microsomal delta4-3-ketosteroid-5alpha-reductase and 17beta-hydroxysteroid oxidoreductase enzymes metabolizing testosterone. Systemic administration of medroxyprogesterone acetate further increased this cytosolic activity.





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IADR Journals Advances in Dental Research ®
Journal of Dental Research ® Critical Reviews (1990-2004)
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