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Journal of Dental Research, Vol 56, 1097-1105, Copyright © 1977 by International & American Associations for Dental Research Online Journals

ARTICLES

Levan production by a strain of Rothia: activation of complement resulting in cytotoxicity for human gingival cells

R. J. Lesher and V. F. Gerencser

An extracellular polysaccharide identified as a levan has been isolated from Rothia dentocariosa, strain 477 serotype 2. The levan produced by strain 477 has been found to activate the complement cascade in the absence of specific antibodies. This activation was found to be cytotoxic for human gingival cells in tissue culture.




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