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Journal of Dental Research, Vol 56, 1007-1012, Copyright © 1977 by International & American Associations for Dental Research Online Journals

ARTICLES

Collaborative evaluation of a rat caries model in six laboratories

R. H. Larson, S. M. Amsbaugh, J. M. Navia, S. Rosen, G. S. Schuster and J. H. Shaw

When highly controlled parallel rat caries studies were run simultaneously in six laboratories, a similar pattern of caries developed in every laboratory with a range in mean values such that the results of no investigator were significantly different from those of at least two others. These results indicate that the major factors influencing development of rat caries have been recognized and can be controlled within reasonable limits.




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