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Journal of Dental Research, Vol 56, 739-743, Copyright © 1977 by International & American Associations for Dental Research Online Journals

ARTICLES

Apparent cytotoxicity of base metal casting alloys

R. D. Woody, E. F. Huget and J. E. Horton

The cytotoxic potentials of three Ni-Cr based alloys and an Fe-Cr based alloy were assessed. In tissue culture, casting of all four test materials and powders of the Fe-Cr based material did not elicit adverse cellular changes. However, cultures containing Ni-Cr powders showed prominent zones of lysis and cell alteration. The cytotoxic potential of products obtained from the surfaces of casting alloys may offer an expedient means for estimation of long-term clinical toxicity.




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